# AWG PD and Brain Aging Subgroup **URL:** \ **Category:** Brain AWG Topics\ **Tags:** subgroup, parkinsons\ **Created:** [June 12, 2025, 10:09pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980 "2025-06-12T22:09:19Z")\ **Posts on this page:** 20\ **Page:** 1
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [June 12, 2025, 10:09pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/1 "2025-06-12T22:09:19Z")
Hi everyone, I’m excited to invite you to join the **AWG PD subgroup** , with the goal of making it more accessible to the broader scientific community. We focus on the analysis of **multi-omics data from spaceflight** and its comparison with **Parkinson’s disease (PD) patient data** from **MJFF’s** **PPMI** and other publicly available datasets, with a strong emphasis on **brain aging and PD-like neurodegenerative risk**. Our subgroup was launched in early 2024 and brings together researchers interested in effect of exposome, such as **microgravity and radiation** on the brain, **PD biomarkers** , and **aging-related vulnerability due to spaceflight environments**. We welcome individuals from diverse backgrounds, including molecular biology, neuroscience, computational biology, AI/ML, and systems medicine. 🧬 **What we do** : - Analyze omics data from rodent brain, human, and neuronal models exposed to spaceflight and space analog stressors - Compare these findings to clinical PD datasets to identify convergent molecular signatures - Curate custom **PD and aging-related pathways** - Explore data-driven hypotheses on the intersection of **radiation, aging, and neurodegeneration** We already have several active and upcoming projects—some open to new collaborators—and are working on multiple publications. 📚 **Here’s a link** to recent **publications and presentations** on this topic from our subgroup and my lab. [https://www.nature.com/articles/s41526-024-00457-6](https://www.nature.com/articles/s41526-024-00457-6) > **[40th Annual Meeting for the American Society for Gravitational and Space...](https://www.xcdsystem.com/asgsr/program/EtF80Tm/index.cfm?pgid=3028&sid=29257&abid=110909)** > **[Studying Parkinson's Disease-Like Molecular Changes in Dopaminergic Neurons...](https://scholarworks.boisestate.edu/under_showcase_2025/13/)** > > Space flight (SF) exposes astronauts to various stressors, including microgravity, cosmic radiation, hypercapnia, ischemia, isolation, and confinement, the long-term effects of which have been linked to the onset of neurodegenerative disorders such... [![](https://us1.discourse-cdn.com/flex001/uploads/osdr/original/2X/2/2c82f043812e7ab7fbf297e3cf7164d5aa6bf263.jpeg "2024 AWG Symposium Day 1 Part 2") ](https://www.youtube.com/watch?v=psrO38DP454&t=2671) More exciting work is underway! 🗓 We meet **biweekly on Mondays at 9 AM MST** (subject to change soon) 📩 If you’re interested in joining, contributing, or just learning more, please DM me or email at nilufarali@boisestate.edu. Let’s work together to uncover the shared mechanisms behind PD and spaceflight exposure—and develop strategies to mitigate the risk. [@MultiOmicsAWG](https://awg.osdr.space/groups/multiomicsawg) ---
**Author:** ![Waq](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/waq/32/2311_2.png) [@Waq](https://awg.osdr.space/u/Waq)\ **Post date:** [June 12, 2025, 11:01pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/2 "2025-06-12T23:01:10Z")
Thank you for the invitation. I am particularly interested in this research direction and would be honored to join your team. ---- Replied Message ---- > From | [Nilufar Ali via Open Science Data Repository Analysis Working Groups](mailto:notifications@osdr.discoursemail.com)[notifications@osdr.discoursemail.com](mailto:notifications@osdr.discoursemail.com) | > > - | - | > Date | 06/13/2025 06:47 | > To | [waq15554811171](mailto:waq15554811171@163.com)[waq15554811171@163.com](mailto:waq15554811171@163.com) | > Subject | [Open Science Data Repository Analysis Working Groups] [AWG Projects/Multi-Omics AWG Open Projects] AWG PD and Brain Aging Subgroup | > ![](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/45/217_2.png "nilufarali") | [nilufarali](https://awg.osdr.space/u/nilufarali) AnimalAWG > June 12 | > > - | - | Hi everyone, I’m excited to invite you to join the AWG PD subgroup, with the goal of making it more accessible to the broader scientific community. We focus on the analysis of multi-omics data from spaceflight and its comparison with Parkinson’s disease (PD) patient data from MJFF’s PPMI and other publicly available datasets, with a strong emphasis on brain aging and PD-like neurodegenerative risk. Our subgroup was launched in early 2024 and brings together researchers interested in effect of … ---
**Author:** ![angel](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/angel/32/49_2.png) [@angel](https://awg.osdr.space/u/angel)\ **Post date:** [June 12, 2025, 11:29pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/3 "2025-06-12T23:29:51Z")
Hello, I developed a very accurate tool for identifying brain pathologies based on resting-state EEG. In fact, it works very well for Parkinson’s, and since it’s EEG, it’s very cheap, simple, and allows for highly precise identification of states in real time. This would make experiment design and data cross-referencing with other methods much easier. Here’s the link: > [@Diagnosis of Alzheimer’s Disease, Parkinson’s Disease, Frontotemporal Dementia, and Paranoid Schizophrenia via Complex Network Analysis of EEG Data](https://awg.osdr.space/t/diagnosis-of-alzheimer-s-disease-parkinson-s-disease-frontotemporal-dementia-and-paranoid-schizophrenia-via-complex-network-analysis-of-eeg-data/2471): > > I’ve developed a method for diagnosing brain pathologies with high precision, achieving the following diagnostic accuracies: Paranoid Schizophrenia: 96% Alzheimer's Disease: 97% Frontotemporal Dementia: 96% Parkinson's Disease: 96% I hope you find it useful: ---
**Author:** ![AstroJac](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/astrojac/32/1005_2.png) [@AstroJac](https://awg.osdr.space/u/AstroJac)\ **Post date:** [June 12, 2025, 11:43pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/4 "2025-06-12T23:43:09Z")
Could I please ask how this is different to the brain ageing and Alzheimers group? I just don’t want to double up my time is all as I’m calling in from Australia. ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [June 13, 2025, 12:46am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/5 "2025-06-13T00:46:32Z")
Wonderful! ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [June 13, 2025, 12:47am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/6 "2025-06-13T00:47:17Z")
Thanks for sharing this! ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [June 13, 2025, 12:54am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/7 "2025-06-13T00:54:14Z")
Hi, this is the PD sub group and we are looking at curated hallmark aging pathways from PD patients data, PD specific brain regions of mice and comparing them post spaceflight. And I believe Joe is leading the work on sex-specific aging related changes in the AD sub group. ---
**Author:** ![NSolomon](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nsolomon/32/2366_2.png) [@NSolomon](https://awg.osdr.space/u/NSolomon)\ **Post date:** [June 13, 2025, 12:59am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/8 "2025-06-13T00:59:24Z")
Hi! It’s so great to meet you. I’d be excited to join your team, this project really aligns with my previous research experiences, and I’d love to contribute. ---
**Author:** ![Hasret](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/hasret/32/1825_2.png) [@Hasret](https://awg.osdr.space/u/Hasret)\ **Post date:** [June 13, 2025, 6:43am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/9 "2025-06-13T06:43:59Z")
Hello Nilufar, I would like to contribute to the Parkinson’s Disease subgroup. Thank you for your consideration and time. Kind regards, Hasret ---
**Author:** ![ccnaney](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/ccnaney/32/747_2.png) [@ccnaney](https://awg.osdr.space/u/ccnaney)\ **Post date:** [June 15, 2025, 5:22am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/10 "2025-06-15T05:22:35Z")
I would be interested in joining to learn more about how I can help advance this interesting new AWG. ---
**Author:** ![met4t](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/met4t/32/569_2.png) [@met4t](https://awg.osdr.space/u/met4t)\ **Post date:** [June 16, 2025, 4:46pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/11 "2025-06-16T16:46:59Z")
I hereby inform of my interest to join the group. I have interest in identifying pathways, biomarkers, and representative classifier genes from analyses of omics data – RNA-Seq, microarray, … ---
**Author:** ![Fgaze](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/fgaze/32/2012_2.png) [@Fgaze](https://awg.osdr.space/u/Fgaze)\ **Post date:** [June 17, 2025, 11:06pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/12 "2025-06-17T23:06:10Z")
Hi Nilufar, I would like to contribute to the Parkinson’s Disease subgroup. Please add me to the group also. Is there any monthly meeting also? Thank you ---
**Author:** ![Wilester2025](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/wilester2025/32/2219_2.png) [@Wilester2025](https://awg.osdr.space/u/Wilester2025)\ **Post date:** [June 18, 2025, 12:00am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/14 "2025-06-18T00:00:55Z")
Hi also wondering if there was any way I could contribute ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [June 19, 2025, 8:52pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/15 "2025-06-19T20:52:31Z")
Hi, welcome aboard! I look forward to seeing you in our next Zoom meeting. Please see the calendar link posted above. Thanks! ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [June 30, 2025, 5:10pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/16 "2025-06-30T17:10:43Z")
Hi all, Thank you for attending the Zoom meeting today. Here is the link to the member’s list. New members please add your names and other details here: [https://docs.google.com/spreadsheets/d/1WajNl7\_R-DrNJOtauKarNQqGM5d5nUtygJd-dq3FaY4/edit?gid=0#gid=0](https://docs.google.com/spreadsheets/d/1WajNl7_R-DrNJOtauKarNQqGM5d5nUtygJd-dq3FaY4/edit?gid=0#gid=0) I will include you in the follow up emails. Regards, Nilufar ---
**Author:** ![Marc-DenielTolentino](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/marc-denieltolentino/32/1934_2.png) [@Marc-DenielTolentino](https://awg.osdr.space/u/Marc-DenielTolentino)\ **Post date:** [July 10, 2025, 9:22pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/17 "2025-07-10T21:22:17Z")
Hi Dr. Ali, I would love to contribute to the project if you are accepting more collaborators. My email is mtole014@ucr.edu ---
**Author:** ![rtscott2001](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/rtscott2001/32/5_2.png) [@rtscott2001](https://awg.osdr.space/u/rtscott2001)\ **Post date:** [July 11, 2025, 4:43am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/18 "2025-07-11T04:43:09Z")
Excellent thanks Marc! Welcome to the AWG 😊 Make sure to ping @windymc and @nilufarali ---
**Author:** ![windymc](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/windymc/32/410_2.png) [@windymc](https://awg.osdr.space/u/windymc)\ **Post date:** [July 11, 2025, 4:59am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/19 "2025-07-11T04:59:06Z")
Hi Marc, welcome to the group! Please email me at windymc@stanford.edu if you are interested in helping out with AD research. Otherwise, Nilufar is running the Parkinson’s group and is great to work with too! ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [July 14, 2025, 5:56am UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/20 "2025-07-14T05:56:43Z")
Hi Marc, please join the meeting tomorrow! ---
**Author:** ![nilufarali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/nilufarali/32/217_2.png) [@nilufarali](https://awg.osdr.space/u/nilufarali)\ **Post date:** [July 23, 2025, 4:58pm UTC](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980/21 "2025-07-23T16:58:13Z")
Hi All, Due to my travel I have rescheduled our Monday’s meeting to Friday August 1st from 11:30 AM -12:30 PM (MST). Please join using this link- [Launch Meeting - Zoom](https://boisestate.zoom.us/j/96315334276?pwd=BgNqY4Uu2Bw0H1vnbm1FFKaqHUa3XE.1) Meeting ID: 963 1533 4276 Passcode: 228004 One tap mobile +13462487799,96315334276# US (Houston) +16694449171,96315334276# US Find your local number: [Zoom International Dial-in Numbers - Zoom](https://boisestate.zoom.us/u/alcowLDJ9) Cheers, -Nilufar [Next page](https://awg.osdr.space/t/awg-pd-and-brain-aging-subgroup/2980.md?page=2)