# Congrats to the Brain AWG on its first 100% AWG-driven subgroup publication **URL:** \ **Category:** Brain AWG Topics\ **Tags:** publication, new-paper, brainawg, microglia, osd-613\ **Created:** [September 10, 2026, 5:02pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588 "2026-09-10T17:02:07Z")\ **Posts on this page:** 12\ **Page:** 1
**Author:** ![rtscott2001](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/rtscott2001/32/5_2.png) [@rtscott2001](https://awg.osdr.space/u/rtscott2001)\ **Post date:** [September 10, 2026, 5:02pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/1 "2026-09-10T17:02:08Z")
## πŸŽ‰ First Fully Brain AWG-Driven Publication is Out! Congratulations to @dpiekarskiva @windymc @Joseph_Guarnieri @shehbeelarif @dr.aslinger on the [@BrainAWG](https://awg.osdr.space/groups/brainawg) first fully AWG-driven publication: **Spaceflight Modulates Neurodegeneration-Associated Transcriptomic Pathways Across Brain Cell Types** Piekarski, Guarnieri, Arif, Aslinger, McNerney. _Life Sciences in Space Research_ (2026). DOI: [https://doi.org/10.1016/j.lssr.2026.08.007](https://doi.org/10.1016/j.lssr.2026.08.007) Using single-nucleus RNA-seq on brain tissue from OSD-613 (mice flown 55–58 days aboard the ISS; RRRM-2, also known as Rodent Research-17 [RR-17]), the team found that spaceflight drives widespread transcriptional changes across all major brain cell types, with signatures pointing toward oxidative stress, proteostasis disruption, and mitochondrial dysfunction. Microglia in particular shifted toward disease-associated and inflammatory states. ![image](https://us1.discourse-cdn.com/flex001/uploads/osdr/original/2X/4/4978f1622c4aa2a5e839bcd5d7b552c09fa9c797.jpeg) This work grew directly out of Brain AWG discussions, exactly the kind of subgroup-to-publication pipeline we want to see more of. Nice work all around πŸ’― Attached: [Piekarski 2026 LSSR brain scRNA.pdf](https://awg.osdr.space/uploads/short-url/9y2oYQEAdMVuuOh5h16ljtBFdjx.pdf) (2.9 MB) Read the full paper: [https://www.sciencedirect.com/science/article/pii/S2214552426001240](https://www.sciencedirect.com/science/article/pii/S2214552426001240) [@AWGall](https://awg.osdr.space/groups/awgall) ---
**Author:** ![mariannavarro](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/mariannavarro/32/1754_2.png) [@mariannavarro](https://awg.osdr.space/u/mariannavarro)\ **Post date:** [September 10, 2026, 6:02pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/2 "2026-09-10T18:02:38Z")
Congratulations @dpiekarskiva @windymc @Joseph_Guarnieri @shehbeelarif and @dr.aslinger, huge accomplishment!! Can’t wait to read the paper 😁 ---
**Author:** ![anuiris](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/anuiris/32/1358_2.png) [@anuiris](https://awg.osdr.space/u/anuiris)\ **Post date:** [September 10, 2026, 7:20pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/3 "2026-09-10T19:20:40Z")
Congrats to all authors!! ---
**Author:** ![Divyanjali](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/divyanjali/32/4706_2.png) [@Divyanjali](https://awg.osdr.space/u/Divyanjali)\ **Post date:** [September 10, 2026, 7:25pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/4 "2026-09-10T19:25:26Z")
Congratulations 🎊 ---
**Author:** ![AstroJac](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/astrojac/32/1005_2.png) [@AstroJac](https://awg.osdr.space/u/AstroJac)\ **Post date:** [September 10, 2026, 7:45pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/5 "2026-09-10T19:45:37Z")
Wooohooo huge congratulations! Go team! ---
**Author:** ![GasMan](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/gasman/32/2042_2.png) [@GasMan](https://awg.osdr.space/u/GasMan)\ **Post date:** [September 11, 2026, 6:41am UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/6 "2026-09-11T06:41:59Z")
Got to love it, awesome stuff! ---
**Author:** ![Vedika](https://avatars.discourse-cdn.com/v4/letter/v/7feea3/32.png) [@Vedika](https://awg.osdr.space/u/Vedika)\ **Post date:** [September 11, 2026, 4:38pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/7 "2026-09-11T16:38:51Z")
Congratulations on this wonderful achievement! ---
**Author:** ![SirlaneBioQuantica](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/sirlanebioquantica/32/1684_2.png) [@SirlaneBioQuantica](https://awg.osdr.space/u/SirlaneBioQuantica)\ **Post date:** [September 12, 2026, 2:58pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/8 "2026-09-12T14:58:20Z")
Congratulations! ---
**Author:** ![gichukisimon](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/gichukisimon/32/3175_2.png) [@gichukisimon](https://awg.osdr.space/u/gichukisimon)\ **Post date:** [September 15, 2026, 6:46am UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/9 "2026-09-15T06:46:39Z")
Congratulations ---
**Author:** ![tmn2126](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/tmn2126/32/47_2.png) [@tmn2126](https://awg.osdr.space/u/tmn2126)\ **Post date:** [September 16, 2026, 12:14pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/10 "2026-09-16T12:14:55Z")
Congrats! πŸ™Œ ---
**Author:** ![robertsb21](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/robertsb21/32/1055_2.png) [@robertsb21](https://awg.osdr.space/u/robertsb21)\ **Post date:** [September 16, 2026, 12:41pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/11 "2026-09-16T12:41:04Z")
Big win! Congrats everyone!! ---
**Author:** ![jkchau](https://sea1.discourse-cdn.com/flex001/user_avatar/awg.osdr.space/jkchau/32/4750_2.png) [@jkchau](https://awg.osdr.space/u/jkchau)\ **Post date:** [September 16, 2026, 5:17pm UTC](https://awg.osdr.space/t/congrats-to-the-brain-awg-on-its-first-100-awg-driven-subgroup-publication/4588/12 "2026-09-16T17:17:03Z")
Congratulations to all the authors. Cheers to the AWG group!