Solicitation Number: NNJ26ZSA002L
Release Date: March 20, 2026
Response Date: April 15, 2026
The Human Research Program (HRP) investigates and mitigates the highest risks to astronaut health and performance in exploration missions. The goal of the HRP is to provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration, and to ensure safe and productive human spaceflight. The scope of these goals includes both the successful completion of exploration missions and the preservation of astronaut health over the life of the astronaut.
HRP has developed an Integrated Research Plan (IRP) to describe the requirements and notional approach to understanding and reducing the risks to human health and performance. The IRP describes the Program’s research activities that are intended to address the needs of human space exploration and serve HRP customers. The IRP illustrates the HRP’s research plan through the timescale of exploration missions of extended duration.
The Human Research Roadmap (HRR - https://humanresearchroadmap.nasa.gov) is a web-based version of the IRP that allows users to search HRP risks, gaps, and tasks.
The NASA Human Research Program (HRP) is requesting information on existing methods and capabilities to analyze and interpret data that will be collected as part of the Artemis II mission.
NASA is interested in capabilities to utilize clinically relevant data that are collected as part of the Artemis mission.
Appropriate responses to this RFI should address:
-
Recommendations for development and validation of approach(es) to surveil, reduce risk of, and/or treat VT during spaceflight and exploration missions, including rationale and methodology. Approaches might include technologies currently available and those in development as well as applications in low-Earth orbit and during missions to the Moon and Mars where capabilities may be further constrained by vehicle stowage limitations, power allocations, and real-time communication delays with increasing need for Earth-independent operations.
-
If applicable, recommendations for future spaceflight and spaceflight analog research relevant to VT during spaceflight and exploration missions. Relevant applications might include short- and long-duration missions in low-Earth orbit, missions beyond low-Earth orbit, and habitation in partial gravity environments. Analogs might include relevant patient populations, parabolic flight, and suborbital flight.
The full text of the RFI and response instructions can be found at: https://tinyurl.com/VTRFI
Responses must be submitted electronically using the NSPIRES website.
The information obtained will be used by NASA for planning and acquisition strategy development. NASA will use the information obtained through this RFI on a non-attribution basis. Providing data and information that is limited or restricted for use by NASA for that purpose would be of very little value and such restricted/limited data/information is not solicited. No information or questions received will be posted to any website or public access location. NASA may respond to the individual responses.
The Government does not intend to grant an award on the basis of this RFI or to otherwise pay for the information solicited.
Questions concerning this RFI may be addressed to:
NASA Human Research Program Chief Scientist