Event: Horizons in Biosciences & Informatics Seminar Series (HBISS)
What: Precision Medicine through Leveraging Clinical and Molecular Data to Advance Women’s Health
When: April, 25th,12p-1p, PT
Where: BMSIS Zoom
Who: Marina Sirota & Tomiko Oskotsky, UCSF
HBISS Series:
The purpose of the Horizons in Biosciences and Informatics Seminar Series (HBISS) is to foster interdisciplinary conversation, education, and collaboration. Experts in biosciences and informatics are invited to speak once a month and engage with members of the Open Science Data Repository’s Analysis Working Group (OSDR-AWG) and the public, to facilitate discussion of cutting-edge research, techniques, and methodology. Previous HBISS events are listed here.
Abstract:
In this talk, our speakers will describe how they use various omics data as well as electronic medical records and advanced integrative computational approaches to develop diagnostic and therapeutic strategies to better understand women’s health. We will focus on reproductive health including adverse pregnancy outcomes such as preterm birth. They will also discuss the benefits of data sharing and crowdsourcing approaches and impact on education of the next generation of researchers.
Biography:
Marina Sirota, PhD, is currently a Professor and the Acting Director at the Bakar Computational Health Sciences Institute at UCSF. Prior to that she has worked as a Senior Research Scientist at Pfizer where she focused on developing Precision Medicine strategies in drug discovery. She completed her PhD in Biomedical Informatics at Stanford University. Dr. Sirota’s research experience in translational bioinformatics spans nearly 20 years during which she has co-authored over 170 scientific publications. Her research interests lie in developing computational integrative methods and applying these approaches in the context of disease diagnostics and therapeutics with a special focus on women’s health. The Sirota laboratory is funded by NIA, NLM, NIAMS, Pfizer, March of Dimes and the Burroughs Wellcome Fund. As a young leader in the field, she has been awarded the AMIA Young Investigator Award in 2017. She leads the UCSF March of Dimes Prematurity Research Center at UCSF as well as co-directs ENACT, a center to study precision medicine for endometriosis. Dr. Sirota also is the founding director of the AI4ALL program at UCSF, with the goal of introducing high school girls to applications of AI and machine learning in biomedicine. Her Google Scholar is here, and several pertinent references for this talk: Vora et al. 2018; Giudice et al. 2023, Golob et al. 2024, Tang et al., 2024.
Tomiko Oskotsky, M.D. is a physician-scientist in the Sirota Lab at the Bakar Computational Health Sciences Institute, University of California, San Francisco (UCSF). She earned her B.S. in Biochemistry from UCLA and her M.D. from the Medical College of Wisconsin, where she was elected to the Alpha Omega Alpha (AOA) National Medical Honor Society. Her research involves interrogating diverse datasets, including electronic health records, to better understand human health and disease. Her leadership roles include co-leading the March of Dimes preterm birth research data repository and co-directing the UCSF AI4ALL program, which teaches AI to underrepresented youth. Her Google Scholar is here, and couple pertinent references for this talk: Parraga-Leo et al. 2024; Oskotsky et al., 2022.
Questions? Please contact Ryan Scott @rtscott2001 Lauren Sanders @lauren.sanders Sylvain Costes @svcostes
(ryan.t.scott@nasa.gov; lmh.sanders@gmail.com; svcostes@gmail.com)
@AIMLawg @ALSDAawg @MicrobesAWG @FemaleReproAWG @MultiOmicsAWG @AnimalAWG @HUMANawg @PlantAWG @RLWG
https://us02web.zoom.us/j/85983328714?pwd=VaOG5UTzjEeEunVnDiWPtwsrogUtFv.1
Meeting ID: 859 8332 8714
Passcode: 584921