Hi AWG members, this is a longstanding listserve of articles relevant to space biology, space health, etc
@ALSDAawg @AnimalAWG @AIMLawg @PlantAWG @RLWG @FemaleReproAWG @MultiOmicsAWG @MicrobesAWG @HUMANawg
Everything below is directly from that listserve:
————————————
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence or request to unsubscribe to Shawna Byrd, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.
Papers deriving from NASA support:
1
Lee SMC, Ribeiro LC, Martin DS, Laurie SS, Zwart SR, Chen X, Young M, Crucian B, Smith SM, Macias BR.
Arterial structure and function in the years after long-duration spaceflight.
J Appl Physiol (1985). 2025 Apr 30. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/40304245
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 3.3
Funding: “The authors appreciate the astronaut volunteers for their participation; the members of the Cardiovascular and Vision Laboratory, particularly Sondra Perez, Rebecca Cox and Monica Randall, the Nutritional Biochemistry Laboratory, and the Immunology Laboratory at Johnson Space Center for data collection and analysis; the ISS Biochemical Profile Experiment, from which much of the biomarker data reported here were shared; the Research Operations Integration Element, particularly Kelly Norwood, Michelle Lawless, and Pasha Morshedi, for the coordination of pre-, in-, and postflight data collection sessions; and the advice and support of the Lifetime Surveillance of Astronaut Health, particularly Jacqueline Charvat, PhD. This study was funded by the NASA Human Research Program.”
2
Allred AR, Gopinath AR, Clark TK.
Validating sensory conflict theory and mitigating motion sickness in humans with galvanic vestibular stimulation.
Commun En. 2025 Apr 27;4(1):78.
https://doi.org/10.1038/s44172-025-00417-2
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by a NASA Space Technology Graduate Research Opportunities Award.”
3
Cordero RJB, de Groh KK, Dragotakes Q, Singla S, Maurer C, Trunek A, Chiu A, Hwang J, Crowell S, Benyo T, Thon SM, Rothschild LJ, Dhinojwala A, Casadevall A.
Radiation protection and structural stability of fungal melanin polylactic acid biocomposites in low Earth orbit.
Proc Natl Acad Sci USA. 2025 Apr 28;122(18):e2427118122.
https://pubmed.ncbi.nlm.nih.gov/40294260
Journal Impact Factor: 9.4
Funding: “The research was supported in part by the Space@Hopkins Seed Grant and the Air Force Office of Scientific Research FA9550-23-1-0589. A.C. is partially supported by grants R01 AI152078, R01 HL059842, AI171093, and AI052733. We are also grateful to the NASA Innovative Advanced Concepts (NIAC) program for their continued enthusiasm around fungal materials in space, most recently through their Phase 3 award ‘Mycotecture off Planet: En route to the Moon and Mars’ (24-24NIACProp-0008), which supported L.J.R.'s participation in this work.”
4
Doorly R, Ong J, Waisberg E, Sarker P, Zaman N, Tavakkoli A, Lee AG.
Applications of generative adversarial networks in the diagnosis, prognosis, and treatment of ophthalmic diseases.
Graefes Arch Clin Exp Ophthalmol. 2025 Apr 22. Review.
https://pubmed.ncbi.nlm.nih.gov/40263170
PI: A. Tavakkoli
Note: This article may be obtained online without charge.
Journal Impact Factor: 2.4
Funding: “NASA Grant [80NSSC20K183]: A Non-intrusive Ocular Monitoring Framework to Model Ocular Structure and Functional Changes due to Long-term Spaceflight.”
5
Makino Y, Hodgson NW, Doenier E, Serbin AV, Osada K, Artoni P, Dickey M, Sullivan B, Potter-Dickey A, Komanchuk J, Sekhon B, Letourneau N, Ryan ND, Trauth J, Cameron JL, Hensch TK.
Sleep-sensitive dopamine receptor expression in male mice underlies attention deficits after a critical period of early adversity.
Sci Transl Med. 2024 Oct 9;16(768):eadh9763.
https://pubmed.ncbi.nlm.nih.gov/39383245
Journal Impact Factor: 15.8
Funding: “Funding for this study was provided by the Bezos Foundation (to T.K.H.); JPB Foundation (to T.K.H.); NIMH Silvio Conte Center (1P50MH094271) (to T.K.H.); NASA NSCOR grant (to T.K.H.); Canadian Institute for Advanced Research (to T.K.H.); the Broad Trauma Initiative (to T.K.H.); World Premier International (WPI) Research Center Initiative of the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) (to T.K.H.); Kakenhi (20A303) from the Japan Society for the Promotion of Science (JSPS) (to T.K.H.); JSPS Kakenhi (23K06010) (to Y.M.); Takeda Science Foundation (to Y.M.); postdoctoral fellowships from JSPS and the Uehara Memorial Foundation (to Y.M.); grants from the University of Pittsburgh CTSI PINCH pilot, NSF (3644507) (to J.L.C.); and the Palix Foundation and Seacay Corporation (to J.L.C.).”
Other papers of interest:
1
Gilbert AQ.
Astronaut nuclear safety: A concept for managing crew risks when using space nuclear power systems.
J Space Saf Eng. 2025 Apr 23.
https://doi.org/10.1016/j.jsse.2025.04.006
2
Ghani F, Zubair AC.
Possible impacts of cosmic radiation on leukemia development during human deep space exploration.
Leukemia. 2025 Apr 24. Review.
https://pubmed.ncbi.nlm.nih.gov/40275072
3
Möller FN, Hoffmann U, Fomina E, Steinberg F, Koschate-Storm J, Petersen LG.
Monitoring cardiorespiratory and cognitive performance during simulated spaceflight.
Acta Astronaut. 2025 Aug;233:242-9.
https://doi.org/10.1016/j.actaastro.2025.04.052
Note: From the introduction: “This study investigated the feasibility of a monitoring test targeting combined cardiorespiratory fitness and cognition during 120 days of isolation, analyzing results from two isolation analog campaigns with different baseline fitness levels.”
4
Stead T, Blaber AP, Divsalar DN, Xu D, Tavakolian K, Evans J, Billette de Villemeur R, Bareille M-P, Saloň A, Steuber B, Goswami N.
Repeatability of artificial gravity tolerance times.
Front Physiol. 2025 May 1;16:1464028.
https://doi.org/10.3389/fphys.2025.1464028
Note: This article is part of Research Topic “Space Physiology and Medicine: Reports and Unique Data Obtained on Small Sample Sizes” (https://www.frontiersin.org/research-topics/58257/space-physiology-and-medicine-reports-and-unique-data-obtained-on-small-sample-sizes#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,077 https://doi.org/10.3389/fphys.2023.1303938 and https://doi.org/10.3389/fphys.2023.1285802; #1,096 https://doi.org/10.3389/fphys.2024.1369788, #1,102 https://doi.org/10.3389/fphys.2024.1374309; #1,104 https://doi.org/10.3389/fphys.2024.1360353; #1,105 https://doi.org/10.3389/fphys.2024.1375929; #1,116 https://doi.org/10.3389/fphys.2024.1417719; #1,118 https://doi.org/10.3389/fphys.2024.1460131; and #1,125 https://doi.org/10.3389/fphys.2024.1451269. This article may be obtained online without charge.
5
Orford R.
The pioneers of aerospace medicine and what they mean to us.
Aerosp Med Hum Perform. 2025 May 1;96(5):365-6.
https://www.doi.org/10.3357/AMHP.965PP.2025
6
Pauly J, Langlet C, Hainaut J-P, Yusupova A, Bolmont B.
Affective states in a space-analog mission and insights from psychometric and hair cortisol measures.
Aerosp Med Hum Perform. 2025 May 1;96(5):436-42.
https://www.doi.org/10.3357/AMHP.6578.2025
Note: From the abstract: “Long-duration space missions introduce stressors that can disturb the affective states of astronauts (e.g., isolation, workload). However, studies in space or in space-analog environments struggle to find a consensus on the affective impact of these stressors. Also, there is a lack of research using multiple measures to assess affective states in these conditions (e.g., positive and negative measures and physiological parameters). More research is needed to understand the psycho-physiological mechanisms during long-duration space-like missions. Our study was conducted during a space-analog confinement (SIRIUS-19).”
7
Rizzo AM, Murgia G, Lentini A, Zava S, Ferranti F, Tavella S, Santucci D, van Loon J, Colombo I, Corsetto P.
Hypergravity influences mouse erythrocyte membrane lipid composition and antioxidant potential.
Acta Astronaut. 2025 Apr 29. Online ahead of print.
https://doi.org/10.1016/j.actaastro.2025.04.061
Note: From the abstract: “To support safe human space exploration, it is important to understand how different effectors, including gravitational forces, influence living organisms. Indeed, altered levels of gravity affect the physiological function of multiple cells, tissues, and organs in living organisms. Previous studies suggested that microgravity modifies plasma membrane permeability and cellular metabolism in erythrocyte, modifying cholesterol and phospholipid levels. However, to support human safe space exploration, it is also relevant to understand the effects of hypergravity. Therefore, the aim of this study was to investigate in vivo the impact of hypergravity on lipid phenotype and oxidative stress in mice erythrocytes.”
8
Ax T, Bothe TL, Craig JP, Dean SJ, March de Ribot F, Fries FN, Jensen SO, Millar T, Seitz B.
The effect of short-term microgravity and hypergravity on eyelid and brow position.
Orbit. 2025 Apr 23;1-9. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/40265683
Note: From the abstract: “Healthy participants (n = 13; 37 ± 10 years) underwent short-term exposure to microgravity and hypergravity during parabolic flight. Facial images were captured and differences in measurements from pupil center to upper and lower eyelid margins (MRD1 and MRD2), and to the inferior and superior eyebrow margin (PTBi and PTBs) under normogravity, microgravity, and hypergravity were compared. A repeated measures ANOVA with Bonferroni-Holm corrected post-hoc paired t-test was used for statistical analysis.” This article may be obtained online without charge.
9
Al Kuwaiti M, Al Mansoori S, Al Saedi N, Al Shamsi A, Kuhail MA, Ng T, Berengueres J.
Enhancing astronaut cognitive performance: The impact of TENS feedback in spacesuits.
In: Lorenz P, ed. Frontiers of Computer Science and Information Technology. Cham Switzerland: Springer Nature Switzerland, 2025. p. 19-28.
https://doi.org/10.1007/978-3-031-88649-2_3
10
Wang M, Xue J, Liu S, Xu C, Cao Z, Yu H, Nong X, Huang K, Hu S, Guo Y, Han B.
Mechanisms of pyroptosis in modulating osteoblast function under simulated microgravity.
BMC Musculoskelet Disord. 2025 Apr 24;26(1):406.
https://pubmed.ncbi.nlm.nih.gov/40275265
Note: A rotary cell culture system was used to simulate microgravity.
11
Weber BM, Panzirsch M, Pleintinger B, Stelzer M, Arand S, Schöttler C, Bayer R, Hagengruber A, Proske U.
Disturbances in human position sense during alterations in gravity: A parabolic flight experiment.
Exp Brain Res. 2025 Apr 25;243(5):127.
https://pubmed.ncbi.nlm.nih.gov/40278861
Note: This article may be obtained online without charge.
12
Beka SG, Griffiths RF, Myers JA, Skirrow PM.
Appropriate screening tests to assess post-COVID-19 cognitive dysfunction in aeromedical settings.
Aerosp Med Hum Perform. 2025 May 1;96(5):414-24.
https://www.doi.org/10.3357/AMHP.6500.2025
13
Chen L, Chen X, Huo R, Xu S, Xu W.
Astronaut dose coefficients calculated using GEANT4 and comparison with ICRP123.
Radiat Environ Biophys. 2025 Apr 29.
https://pubmed.ncbi.nlm.nih.gov/40298992
Note: This article may be obtained online without charge.
14
Tremblay M, Xu D, Verma AK, Goswami N, Blaber AP.
Alterations in blood pressure dependent activation of leg muscles during standing following bedrest mimic those observed with ageing.
Front Physiol. 2025 Apr 28;16:1426648.
https://doi.org/10.3389/fphys.2025.1426648
Note: This article may be obtained online without charge.
15
Rafieian M, Farbu EH, Höper AC, Valtonen R, Hyrkäs-Palmu H, Perkiömäki J, Crandall C, Jaakkola J, Ikäheimo T.
Blunted cardiovascular responses in individuals with type 2 diabetes and hypertension during cold and heat exposure.
Front Physiol. 2025 Apr 27;16:1558471.
https://doi.org/10.3389/fphys.2025.1558471
Note: This article may be obtained online without charge.
16
Ranieri M, Venneri M, Storlino G, Ferrulli A, D’Agostino M, Centrone M, Di Mise A, Zerlotin R, Tamma G, Grano M, Valenti G.
Alteration of vasopressin-aquaporin system in hindlimb unloading mice.
Front Physiol. 2025 Apr 15;16:1535053.
https://pubmed.ncbi.nlm.nih.gov/40303591
Note: This article is part of Research Topic “74th Annual Meeting of the Italian Society of Physiology: Breakthroughs and Key Discoveries” (https://www.frontiersin.org/research-topics/66738/74th-annual-meeting-of-the-italian-society-of-physiology-breakthroughs-and-key-discoveries/articles) and may be obtained online without charge.
17
Moussa MS, de Vet T, Lebcir N, Zaslansky P, Chalifour LE, Willie BM, Komarova SV.
Botulinum toxin (a) -induced bone loss is associated with increased blood velocity and reduced vascular bone porosity.
J Bone Miner Res. 2025 Apr 24;zjaf057. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/40272396
Note: From the abstract: “Disuse-induced bone loss is a common consequence of spaceflight and prolonged bed rest. Intraosseous blood vessel volume and number are decreased in rodents after sciatic nerve resection, and femoral and tibial perfusion and blood flow to the femoral shaft and marrow are reduced after hindlimb unloading. However, it is unclear if alterations in the flow of blood contribute to botulinum toxin (BTX)-induced bone loss. The objective of this study was to assess patterns of tibial bone loss and alterations in blood flow in murine hindlimbs following BTX injection.” This article may be obtained online without charge.
