SOMA Space Science package FemaleRepro Papers

AWG Discussions FemaleRepro AWG Topics
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Spaceflight induces changes in gene expression profiles linked to insulin and estrogen: Spaceflight induces changes in gene expression profiles linked to insulin and estrogen | Communications Biology

Understanding how space travel affects the female reproductive system: Understanding how space travel affects the female reproductive system | npj Women's Health

Sex differences on immune cells gene expressions -->Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight: Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight | Nature Communications

Sexual dimorphism during integrative endocrine and immune responses to ionizing radiation in mice: Sexual dimorphism during integrative endocrine and immune responses to ionizing radiation in mice | Scientific Reports

@FemaleReproAWG @ALSDAawg

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Awesome! Thank you for sharing.

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Congratulations on this great work! I am interested to take part in any future work related to women’s health and any reproductive work. Thanks

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Excellent Jean! Just added you to the new Female Repro AWG @FemaleReproAWG - with @abegum @svcostes @busracetinkayaun as organizers/leads

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Very interesting. How do they measure their hormone level in space? (what is the diagnostic approach? immunoassay? real-time analysis?)
Shai

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On Earth: Method: Elisa. Specific days to measure for clinical purposes. For research questions additional data points can be added.

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ELISA, like other types of immunoassays, relies on antibodies to detect a target antigen using highly specific antibody-antigen interactions. Enzyme conjugation with substrates that produce visible products are being used to get results that can be interpreted visually. My question is- if we don’t know how radiation and gravity change are affecting the interaction with the target antigen (hormones in our case) and if we don’t know how the conditions in space effect the enzyme conjugation, how can we rely on the Elisa analysis results?

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