Dear OSDR community,
As part of our work on understanding viral reactivation in neurodegenerative diseases and in astronauts, the Brain AWG is developing software capable of performing virome characterization from a wide range of nucleic acid sequencing data. This includes automtic virus genome assemblies, classification, annotation, quality validation, and quantification.
Although the tool was initially designed to assess virus reactivation, it is being generalized for use with diverse sample types. So far, it has been successfully tested on AD patient blood samples, COVID-19 patient samples, crustatian samples, and wastewater datasets. The software supports bulk RNA/DNA sequencing, short reads (paired-end and single-end), long reads, and single-cell RNA-seq.
We are now seeking contributors to help us test the software and provide feedback. Installation is straightforward on Linux and macOS, while Windows users can run it through the Windows Subsystem for Linux (WSL). The software is currently hosted in a private GitHub repository as we prepare the associated publication.
If you have sequencing data for which you’d like to perform virome characterization, or if you’d like to help by testing the tool on publicly available datasets, we would be deeply grateful. Contributors who meaningfully assist will be offered co-authorship on the upcoming publication.
If you are interested, please contact us via direct message on this platform or by email at: britaniadiazf@gmail.com
Thank you very much for your support and interest!
@ALSDAawg @AnimalAWG @AIMLawg @PlantAWG @RLWG @FemaleReproAWG @MultiOmicsAWG @MicrobesAWG @HUMANawg @BrainAWG @HardwareAWG @PPawg