Amazing read. Perhaps if sensors are to be used as part of the solution than sensor drift over time could become significant. There is a group looking at how to use AI to teach sensors to be more honest
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Thatâs a great pointâsensor drift can significantly affect data reliability in long-duration missions.
Incorporating AI-based drift correction or self-calibration methods could be crucial for maintaining accurate and trustworthy inputs in the CDSS.
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Hi everyone,
I have updated the Problem Research Documentation with relevant research papers and references on CDSS for space missions, as shared by everyone.
Anyone who would like to contribute or add additional studies can update the document as well.
Thank you!
Problem Research Word document: Problem Research - Google Docs
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Thank you for sharing the Google Drive linkâitâs really helpful
Could you kindly share the same link with gallaher@live.co.uk as well?
Thank you once again
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Hi everyone Iâll be wrapping up the meeting in a couple of minutes. If anyone would still like to join, please feel free to do so. Thank you!
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Great. I am interested in being a part of the CDSS group to work on multi-omics data analysis.
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Can you please ( @AliReza-H ) invite me as a collaborator? My GH handle is: @robertn01
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Done - apologies for the delay, havenât looked at OSDR in the past few weeks due to heavy workload. Hope the GDrive share works.
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Hi Robert ,
I added you as contributor to the project github 
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Hi everyone, I am a new OSDR member and would love to be added to any correspondence for the CDSS group. My email is dxia397@gmail.com.
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Hi Dan
You could refer to this post regarding all the resources: Join the CDSS Subgroup! - #19 by Ritika_Saha Also, we have recently started working on I4 mission dataset analysis: you can refer to this excel sheet: I4 Dataset Analysis - Google Sheets as well.
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You can reach out to @AliReza-H or to me directly
Thank you! Looking forward to working together!
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Hi folks! Sorry again if I should post these via another channel/ thread within OSDR AWG CDSS.. (NB: Iâd truly appreciate a WhatsApp channel). Come across two papers - you may or may not be aware - mainly to put all things into context.
- âTechnology modification, development, and demonstrations for future spaceflight medical systems at NASAâ: Frontiers | Technology modification, development, and demonstrations for future spaceflight medical systems at NASA
Future long-duration missions to the Moon and Mars present significant healthcare challenges due to limited vehicle resources, communication delays, and the impossibility of quick evacuation. NASA is currently transitioning from Earth-reliant medical support to a paradigm of crew autonomy, necessitating the development of a cohesive, integrated medical system. This involves identifying and adapting commercial-off-the-shelf technologies - such as portable X-ray machines, multi-functional vital sign monitors, and blood analyzers - to function reliably in microgravity and radiation-heavy environments. Key innovations include the IVGen system for producing sterile fluids from potable water and the AMOS software for providing just-in-time procedural guidance to non-specialist crew members. Ongoing demonstrations on the International Space Station and in terrestrial analogs are essential for maturing these technologies to ensure they can effectively manage illnesses and injuries during deep-space exploration. Development also focuses on digital informatics, such as electronic health records and automated inventory tracking, to sustain medical readiness without real-time ground assistance.
- âThe value of a spaceflight clinical decision support system for earth-independent medical operationsâ: The value of a spaceflight clinical decision support system for earth-independent medical operations - PMC
As NASA transitions toward deep space exploration, astronauts must overcome the challenge of medical independence due to significant communication delays and the impossibility of emergency evacuations. Currently, crews rely on real-time guidance from ground-based flight surgeons, but future long-duration missions will require autonomous health management. To address this, researchers propose implementing a Clinical Decision Support System (CDSS) to augment the crewâs limited medical training. This advanced technology would provide real-time diagnostics, therapeutic guidance, and just-in-time training to help non-physician astronauts manage everything from routine illness to life-threatening trauma. By integrating probabilistic modelling and ambient monitoring, a CDSS could significantly reduce mission risk and improve patient outcomes. Ultimately, such systems serve as a vital cognitive assistant, ensuring that exploration crews can maintain their health while operating far beyond Earthâs immediate support.
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Hi @robertn01
I really love reading those two papers. Honestly, I believe they should serve as the foundation for all our CDSS work, especially the second one! There are several key terms we should focus on, such as ExMC, EIMO, LEO, and CMO. I think these concepts will help us better visualize real-world scenarios and pain points, which will enable us to address the core issues more effectively.
Also, itâs important to note that, in most cases, the CMO is not a physician. Their medical training is very limitedâoften just a few hours! Relying on those skills for long-term missions is a significant challenge. For our first CDSS project, I think tackling this issue should be our main goal.
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I agree, the second paper in particular Robert is so relevant to the project.
I think if we truly imagine the limitations and dangers of deep spaceâand how drastically everything differs from Earth, low orbit, aviation, related to healthcareâweâre pushed to break the problem down to first principles. At that point, creativity naturally emerges as the ultimate solution.
Also i think tele-medicine/surgery will be solved in this problem-solving journey too.
I agree - wish I could read / do more if wouldnât be crazy busy with post-doc/ job hunting.. But here is another paper, which - even tangentially - might be of interest and I think resonates well with what have been just âsaidâ (+ following up on the first article).
âAutonomous Medical Officer Support Software Technology Demonstrations on the International Space Stationâ
https://journals.sagepub.com/doi/10.1177/15305627261422798
The Autonomous Medical Officer Support (AMOS) software is a specialized digital tool designed to help astronauts perform medical procedures without real-time assistance from Earth. As space missions move further from our planet, the increasing communication delays make traditional ground-guided medicine impossible, requiring crews to be more independent. Researchers tested this system on the International Space Station, where crewmembers successfully used the software to conduct complex kidney and bladder ultrasound examinations with no prior training. The software provides just-in-time instruction through text and video, allowing users to acquire high-quality diagnostic images autonomously. Results from these demonstrations proved that the platform is highly usable and supports a rapid learning curve for non-experts in microgravity. Ultimately, this technology serves as a vital proof-of-concept for maintaining crew health during future long-duration voyages to destinations like Mars.
Also, in the meantime, trying to get involved in astronaut data analysis work incl Artemis II (in my 48-hour days 
).. plus remaining hopeful to be able to tap on the whole Apollo health/ physio data asset at some point..
Speak soon today (it will be 6 pm here in Strasbourg, France..)
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Thanks Robert. Really interesting read. So difficult at times to find a balance to be able to try to do everything when we can only do so much even with 48 hours in a day.
A peripheral but recent article re adjustments to grip strength in 0 G. Relevant perhaps to fine manipulation of something like surgical instruments in space.
Effect of risks, consequences, and gravitational priors on sensorimotor coordination: insights from weightlessness. Laurent Opsomer, Simon Vandergooten, Jean-Louis Thonnard, Joseph McIntyre, Philippe Lefèvre. Journal of Neuroscience 20 April 2026, e2036252026; DOI: 10.1523/JNEUROSCI.2036-25.2026
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Huh /
Nice : âwe can only do so much even with 48 hours in a day.â
Also there is many funny moments caputred from astronuts related to this âCoordination problemâ when they back to earth !
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