Thirty one new RRRM-1/RR-8 datasets in OSDR! MicroRNAs & scRNAseq

New OSDs/data/articles
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:rocket: Thirty-one new RRRM-1/Rodent Research-8 datasets — let the analyses begin!

The release of 31 omics studies from RRRM-1 / RR-8, organized by tissue type, enables systemic, cross-organ comparisons within the same cohort of animals. All data are publicly available in the NASA Open Science Data Repository (OSDR).

13 tissues — miRNAseq + scRNAseq  |  2 tissues — miRNAseq only  |  16 tissues — scRNAseq only

Study 1 — MicroRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM & developmental pathways

OSD Tissue miRNAseq scRNAseq
OSD-904 SCAT (Subcutaneous Adipose Tissue) :check_mark: :check_mark:
OSD-905 Liver :check_mark: :check_mark:
OSD-906 BAT (Brown Adipose Tissue) :check_mark: :check_mark:
OSD-907 Thymus :check_mark: :check_mark:
OSD-908 Heart :check_mark: —
OSD-909 Pancreas :check_mark: :check_mark:
OSD-910 Spleen :check_mark: :check_mark:
OSD-911 GAT (Gonadal Adipose Tissue) :check_mark: :check_mark:
OSD-912 MAT (Mesenteric Adipose Tissue) :check_mark: :check_mark:
OSD-913 Kidney :check_mark: :check_mark:
OSD-914 Diaphragm :check_mark: :check_mark:
OSD-915 Lung :check_mark: :check_mark:
OSD-916 Brain :check_mark: —

Study 2 — Spaceflight induces systemic effects on extracellular matrix and immune system in different age-stages

OSD Tissue miRNAseq scRNAseq
OSD-917 Aorta — :check_mark:
OSD-918 Blood — :check_mark:
OSD-919 Bone (Femurs, Hip Bones, Vertebral Columns) — :check_mark:
OSD-920 Eye — :check_mark:
OSD-921 Heart Atria — :check_mark:
OSD-922 Heart Ventricles — :check_mark:
OSD-923 Large Intestines — :check_mark:
OSD-924 Limb Muscle — :check_mark:
OSD-925 Mammary Gland — :check_mark:
OSD-926 Bone Marrow — :check_mark:
OSD-927 Myeloid Cerebellum — :check_mark:
OSD-928 Myeloid Forebrain — :check_mark:
OSD-929 Myeloid Hippocampus — :check_mark:
OSD-930 Non-Myeloid Cerebellum — :check_mark:
OSD-931 Non-Myeloid Forebrain — :check_mark:
OSD-932 Non-Myeloid Hippocampus — :check_mark:
OSD-933 Skeletal Stem Cells — :check_mark:
OSD-934 Skin — :check_mark:

Click any OSD number to access the dataset directly in OSDR. Questions? Post in this thread or reach out to the OSDR team.

@ALSDAawg @AnimalAWG @AIMLawg @PlantAWG @RLWG @FemaleReproAWG @MultiOmicsAWG @MicrobesAWG @HUMANawg @BrainAWG @HardwareAWG @PPawg

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Thanks @jgalazka

I believe this is the new paper on the miRNAs from the authors of these data:

Grandke, F., Rishik, S., Wagner, V. et al. MiRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM and developmental pathways. Nat Commun 17 , 1387 (2026). https://doi.org/10.1038/s41467-026-68737-1

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God bless you!

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Hey Ryan,

Are these datasets downloadable somewhere? Clicking on them causes the browser to crash, even the links in the paper.

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Indeed, someone else mentioned this last night too.

It may be that the repo is down? Look like at least from Saturday to now Sunday night

@kirill @Danielle.Lopez @jgalazka @aeuriart

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The repository now seems to be back online