RR-18 retina omics analysis: Looking for AWGers to help on analysis

Hi AWG,

Datasets produced by the GeneLab Sample Processing Lab are soon to be released from RR-18 retinas (bulk RNAseq and RRBS), and I am helping to start a new Animal AWG sub-group composed of people with bioinformatic experience to help analyze, visualize, and draw conclusions from the data (in conjunction with my other data from RR18). Does anyone have experience with RRBS data analysis? ( Reduced representation bisulfite sequencing)

The data should be released maybe by October, so not super time senstive, yet, but I wanted to let the AWG know

Here is a payload record from RR18: NASA OSDR: Open Science for Life in Space

This spaceflight study focuses characterization of acute and delayed risks from exposure to space environment to the eye. The project also aims to determine an antioxidant metalloporphyrin protects against spaceflight environment-induced changes in retinal neurovascular coupling and retinal function. Analysis of retina RNAseq and RRBS from these flight samples will help understand the mechanisms of retina injury from exposure to space environment.

Contact: Xiao Wen Mao, xmao@llu.edu or @xmao

Here are other similar datasets in OSDR:

@AnimalAWG @MultiOmicsAWG

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Hello,

I would be interested in participating in this study and helping the project! If you would like to have me how could I assist in this?

Sincerely,
Nathan Pelonis

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Also happy to assist.
Shai

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Pinging a few people who either may be interested to join @xmao in analyzing the data from these RR-18 retinas (explanation above :top:), or know colleagues/bioinformations who may want to join this unique opportunity to help analyze RR-18 data

@jang1563 @asaravia @Dr.Overbey @joel.steele @james.casaletto @naililhusna25 @joseph.j.borg @barbara.novak @georgemias @lauren.sanders @nidiatrovao @xiaojing.dai @obdbotanist @tejaswini.mishra @jgong @chm2042 @stefan_green @Syic @cassianyee @pmadrigal

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Also happy to assist with this (don’t know enough about RRBS and would love to learn)! @xmao

Jian.

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I’d be happy to assist with this project. I haven’t worked with RRBS data, but am experienced with analyzing both bulk and sc-RNA-seq data.

Best regards,
Evan (evanpeikon@gmail.com)

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Hi,

I have some limited experience with RRSB.

I would be happy to help with the analysis.

Sincerely,
Vatsala Tewari

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Hi, @xmao
I am happy to help! I’ve done my BSc diss on collagen associated small proteoglycans and the development of the cornea. I should be ok with the bioinformatic analysis just need to understand the data and the environment. Let me know how I can help!
Kind regards,
Pre

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