Dear AI/ML subgroup @AIMLawg
We just published a paper in JMIR on the use of ML classification models to predict condition (flt vs gc) and age (young vs old) using transcriptomic data (OSD-511) as features. We are working on a similar analysis (using linear regression) for the RR9 retina data (OSD-255, OSD-568, OSD-573).
Casaletto JA, Zhao T, Yeung J, Lee A, Ansari A, Fry A, Mishra A, Raj A, Sun K, Lendahl S, Guan W, Cline MS, Costes SV. Machine Learning Ensemble Investigates Age in the Transcriptomic Response to Spaceflight in Murine Mammary Tissue: Observational Study. JMIRx Bio 2026;4:e73041
doi: 10.2196/73041
There are a lot of other datasets in OSDR to which we can apply these approaches. Please reach out if you’re interested!
cheers and best
-james