AWG Gene: Spaceflight-Induced Mitochondrial Gene Expression Alterations with Relevance to Oral Tissue Homeostasis

Dear Colleagues,

I am writing to invite expressions of interest for a bioinformatics project focusing on “In Silico Analysis of Spaceflight-Induced Mitochondrial Gene Expression Alterations with Relevance to Oral Tissue Homeostasis.”

This project will involve analyzing existing datasets to understand how spaceflight affects mitochondrial gene expression and its implications for maintaining healthy oral tissues. This is a fascinating area with direct relevance to astronaut health and broader applications in understanding mitochondrial function.

We are looking for individuals with a strong background in bioinformatics, computational biology, or a related field. Experience with gene expression analysis, mitochondrial biology, and statistical programming (e.g., R, Python) would be highly beneficial. The work lead to a publication.

If you are interested in contributing to this research, please reply to this email.

We look forward to hearing from you.

Sincerely,
Dr Shahnawaz

@MultiOmicsAWG @MicrobesAWG

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Thanks for posting @khijmatgar

Make sure to attend the upcoming Multi-Omics AWG meeting to present your proposal idea

Before the meeting also reach out to Afshin Beheshti to get on the agenda: beheshti@pitt.edu

Next Multi-Omics AWG meeting is August 20th: https://awg.osdr.space/t/multi-omics-awg-meeting/916

@jessicadurbano

Also, you may want to connect with the @MicrobesAWG lead by @daniela.bezdan which meet on first Wednesday of the month, so Aug 6th: https://awg.osdr.space/t/microbes-awg-meeting/917 Make sure to ping Daniela and Jaume to get on that meeting’s agenda to present your proposed project: bezdan.daniela@googlemail.com and jaume.puig98@gmail.com
@jaume.puig

Plus there is an Oral Microbiome group led by @jonathon_baker @DirkNeefs – I could forsee a cool collaboration across Multi-Omics and Microbes AWGs on this topic :slight_smile:

Thank you!

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Dear @khijmatgar and @rtscott2001 , in the Oral Microbiome subgroup we want to start more projects. .This could be a great opportunity starting one . You could uae the templates @nicholas.brereton has placed in the google drive for that purpose. We can discuss this in our next OM meeting in september. If you want we can have a meeting with @nicholas.brereton and @jonathon_baker prior to initiating your project.
Let me know. You did an excellent job with our ESA Topical Team leading the research together with Massimo del Fabbro and Gianluca Tartaglia. Let us know Shahnawaz, we are open for it!

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Hi I would be interested in contributing let me know if you want me to send over my resume!

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Hi Dirk Thank you very much for your message. Nicholas Brereton has shared the folder with me in relation to the oral microbiome project. I have written few projects on the same. Since the topic here i proposed is more on cell and gene, which is a different approach as compared to microbiome, so i have posted here. But definately, i have uploaded different research questions on the oral microbiome and l look forward to taking some of them as lead and contributing on them.

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Hi Jahnavi,
Thank you for your interest. Sure, we can discuss and explore how you can contribute.
pin me on khijmatgar@gmail.com and we will take it from there.
thanks

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Hi Scott,
Thank you very much for the message and for sure i will attend and will be happy to share the project.

and Thank you for the great references, i will reach out to them. I am in line with the beheshti and they know it is in the pipeline.

I will pin for Aug 6th 2025 to present the project.

thanks you

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Hey Dr Shahnawaz,
I would also love to help with this project! I am still learning, but would be great with any python-based tasks!

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Hi Misha, Thank you for your message and interest. Please email me on khijmatgar@gmail.com and we will discuss.
Thank you

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Dear Dr. Shahnawaz,

Thank you for sharing this exciting opportunity. I am an early-career researcher in molecular biology with foundational training in bioinformatics (currently completing the GL4U RNA-Sequencing course by mid-August). While I am relatively new to the field, I am highly motivated to contribute to this project and further develop my skills in gene expression analysis.

The intersection of mitochondrial biology and spaceflight-related transcriptomics is particularly fascinating to me, and I would welcome the chance to collaborate and learn. Please let me know if there might be a role for a beginner with keen interest, and I would be happy to discuss my background further.

Thank you for your consideration.
Best regards,
Shabbir