AWG 2025: The Year in Review and Looking Forward

Happy new year AWG! Welcome back.

I suggest you scroll below to check out our semi-automated summary of 2025 here on the Forum-Space.

In my opinion, the post started by @marie.mortreux was the post of the year (some wonderful success stories and touching responses on the impact of our AWG community/OSDR-GL data): Appreciation thread for GL, OSDR teams and the AWG, followed by the ~2017 NASA GeneLab video, which fills me with confidence and pride in our community, the science, and the future.

:pushpin: Key Resource: Read the updated AWG About page for ALL quick links to OSDR, GeneLab, tools, trainings, APIs, and resources. In my opinion, this is our most important link to share with anyone anywhere (it also has answers how to join).


AWG Highlights from Open Projects for January 2026

Biofilm Sub-group (Microbes AWG): Article accepted! Cheers to @katherine.j.baxter, @vrvinothan, and all authors @nicholas.brereton! (Details)

Plant-Regolith Sub-group (Plant AWG): Close to publishing a whole book! Looking forward to updates at upcoming @PlantAWG meetings. Cheers @borjabarbero (who leads the sub-group), @Harmeet-Singh, @rachelcrivero, and all. (Details)

Hardware AWG: Getting closer to a manuscript on SPLASH. Kudos to @jessica.a.lee, @kvbrahma, @danielle.lopez91, @ajricco, @AaronPersad, and @aaron.berliner. (Details)

AI/ML AWG: Two projects nearing fruition: the AI-Readiness group led by @pmadrigal (manuscript phase), and the DNA Damage ML Imaging project led by @evartsb (also in manuscript phase?). Cheers all! (AI-Readiness Details; DNA Damage Details)

PP AWG: Getting closer to launching projects, with broader AWG invitations to follow. Cheers to @stefan_green @Haley_Sapers and @Alex who all co-lead the group, along with @Stighe who has stepped up to help.

ALSDA AWG: On hiatus from regular meetings, the assay metadata standards continue though, and of note the ā€˜SOLSTICE’ citizen science manuscript on cardiovascular spaceflight meta-analysis was submitted, with a second manuscript getting closer! Congrats @mattias.neset, cheers @komarova and all involved. Good luck finishing the PhD, Mattias.

Exosome Sub-group (Multi-Omics AWG): Kudos to @kykamal and Abdelraouf Omar. Watch his great talk at the 2025 Annual Symposium (full event: recordings page). (Details)

Brain AWG: There is tremendous activity with projects on viral reactivation, spaceflight brain senescence accumulation, Alzheimer’s & Parkinson’s disease risks, hydrocephalus, and tunneling nanotubes/communication. Cheers to @windymc and @nilufarali for leading that community.

Microbes AWG-Plant AWG Collaboration: Review manuscript is getting closer for submission: ā€œCharting the path forward for plant-microbe systems in space.ā€ Cheers @ben.sikes, @anna.lewkowicz, @eszter.sas, @nicholas.brereton, @nidiatrovao, @LindsayW and all! (Details)


Recent Publications

Paola Castano: Understanding the ā€˜spaceflight treatment’ in plant space biology: Experimental practices, metadata workflows, and data re-analysis. @PCastano also produced this report (Feb '25) from her AWG survey.

Evolution Sub-group (Animal AWG): @fumimuratani, @agata.rudolf & @alexa.sadier published: Evolution in space: experimental pathways to understanding life’s adaptability beyond Earth (details). Well done!! I’ve heard a good bit of positive feedback, it’s a great enticing read.

Miguel Angel Vargas Cruz: @angel Cheers on the new preprint! Architecture of Sintered-Regolith Lunar Polar Microhabitats for Biofilm Research


Ongoing Projects

Proteomic Pipeline Sub-group (Multi-Omics AWG): @asaravia continues quite actively with @joel.steele @hosseinvk Hossein Fazelinia @spruce @terry.lim and all subgroup members for a draft pipeline working with OSDR’s Data Processing team, and are about to begin testing on OSDR datasets. (Details)

NBISC100 sub-group (Animal AWG): @asaravia continues coordinating, along with work with @kuppala @ccnaney @saclayton @nicholas.brereton @emmanuel.gonzalez @keith.siew and all other sub-group members on comparing mRNA (UPX and mRNA kits) and ribodepletion methods. (Details)

RadLab WG & AI/ML AWG: ML project to separate SAA/GCRs led by @martin. Cheers @j_miller, Livio Narici, @kirill, and all. (Details)

Female Repro AWG: Cheers to @abegum @jessicadurbano, @seeratmaqsood, and all other members for their continued assessment of reproductive tissues from the Rodent Research missions.

Anomaly Detection + Environmental Data App: @kjenkins, @aeuriart, @mboerrigter, @rafaelvaz, @lauren.sanders, and others are combining Kenny’s Anomaly Detection tool with the OSDR Environmental Data App. May integrate RR-1 video results from @talmo and @fredkiffer. Exciting stuff! (Details)

Cancer/Spaceflight Risk Analysis (Multi-Omics AWG): @anuiris is about to submit a manuscript she has led for several years. Cheers Anu!


If I didn’t mention your project or sub-group, it was not intentional. I look forward to being kept up-to-date! Always feel free to shoot me a message @rtscott2001 on the Forum-Space.

Cheers and happy new year all,
-Ryan

@ALSDAawg @AnimalAWG @AIMLawg @PlantAWG @RLWG @FemaleReproAWG @MultiOmicsAWG @MicrobesAWG @HUMANawg @BrainAWG @HardwareAWG @PPawg

And here’s our 2025 in Review :slight_smile:

2025's Top Users

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Days Visited Users
344 1
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Users Granted the Thank You Badge

@nicholas.brereton
@ben.sikes
@kykamal
@ccnaney
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@anna.lewkowicz
@jgong
@Jennifer_Claudio
@fumimuratani
@borjabarbero
@paula6
@DirkNeefs
@evartsb
@kajari.das63
And 3 more…

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